Merebaknya wabah Corona di Indonesia menimbulkan korban yang tidak sedikit jumlahnya. Keunikan dari virus Corona (Covid-19) adalah penyebarannya yang terbilang sangat cepat dari satu orang ke orang lain melalui interaksi sosial, atau dengan kata kain dari pasien yang terinfeksi virus ke orang lain melalui komunikasi diantara mereka.

Dalam mendeteksi keberadaan seseorang apakah terinfeksi virus Corona atau tidak, terdapat beberapa metode yang telah dijalankan oleh pihak medis, antara lain metode Rapid test dan Swab test. Rapid test corona hanya bisa digunakan sebagai skrining atau penyaringan awal. Sementara hasil Swab test dapat digunakan sebagai analisa diagnosa bahwa seseorang terinfeksi Covid-19.

Perbedaan Rapid Test Corona Dan Pemeriksaan Swab

Berikut beberapa perbedaan antara tes Rapid dengan pemeriksaan Swab melalui tenggorokan :

1. Jenis sampel yang diambil

Pemeriksaan rapid test dilakukan menggunakan sampel darah. Sedangkan pemeriksaan swab menggunakan sampel lendir yang diambil dari dalam hidung maupun tenggorokan.

2. Cara kerja

Rapid test memeriksa virus menggunakan IgG dan IgM yang ada di dalam darah. Apa itu? IgG dan IgM adalah sejenis antibodi yang terbentuk di tubuh saat kita mengalami infeksi virus. Jadi, jika di tubuh terjadi infeksi virus, maka jumlah IgG dan IgM di tubuh akan bertambah. Hasil rapid test dengan sampel darah tersebut, dapat memperlihatkan adanya IgG atau IgM yang terbentuk di tubuh. Jika ada, maka hasil rapid test dinyatakan positif ada infeksi. Namun, hasil tersebut bukanlah diagnosis yang menggambarkan infeksi Covid-19. Maka dari itu, orang dengan hasil rapid testnya positif, perlu menjalani pemeriksaan lanjutan, yaitu pemeriksaan swab tenggorok atau hidung. Pemeriksaan ini dinilai lebih akurat sebagai patokan diagnosis. Sebab, virus corona akan menempel di hidung atau tenggorokan bagian dalam, saat ia masuk ke tubuh. Sampel lendir yang diambil dengan metode swab nantinya akan diperiksa menggunakan metode PCR (Polymerase Chain Reaction). Hasil akhir dari pemeriksaan ini, nantinya akan benar-benar memperlihatkan apabila ada virus SARS-COV2 (penyebab Covid-19) di tubuh seseorang.

3. Waktu yang diperlukan untuk mendapatkan hasil

Rapid test hanya membutuhkan waktu 10-15 menit hingga hasil keluar. Sementara itu, pemeriksaan menggunakan metode PCR membutuhkan waktu beberapa jam hingga beberapa hari untuk menunjukkan hasil. Hasil pemeriksaan rapid test maupun PCR juga bisa keluar lebih lama dari itu, apabila kapasitas laboratorium yang digunakan untuk memeriksa sampel, sudah penuh. Sehingga, sampel yang masuk harus antre lama untuk bisa diperiksa.

4. Kelebihan dan kekurangan rapid test

Salah satu kelebihan pemeriksaan rapid test adalah tes ini cepat dan mudah untuk dilakukan. Cara ini juga bisa menjadi alternatif skrining cepat untuk mendata orang-orang yang butuh pemeriksaan lanjutan. Kekurangannya, hasil dari tes ini tidak bisa digunakan untuk mendiagnosis Covid-19. Pasien yang positif rapid test harus melalui pemeriksaan lanjutan yaitu Swab. Sementara itu pasien yang negatif, idealnya mengulang rapid test 7-10 hari kemudian. Jika tidak memungkinkan untuk mengulang, maka harus tetap isolasi di rumah selama 14 hari. Mengapa begitu? Karena IgG dan IgM, yaitu antibodi yang diperiksa melalui rapid test, tidak langsung terbentuk begitu Anda terinfeksi. Dibutuhkan waktu kurang lebih 7 hari hingga antibodi tersebut terbentuk. Jadi, kalau Anda menjalani pemeriksaan rapid test hari ini padahal baru terpapar virus corona kemarin, maka kemungkinan besar, hasilnya akan negatif. Inilah yang dinamakan dengan false negative atau negatif palsu. Begitupun saat hasil rapid testnya positif, bisa saja ternyata false positive atau positif palsu. Sebab, IgG dan IgM akan terbentuk setiap infeksi terjadi dan bukan hanya akibat infeksi Covid-19. Jadi, jika rapid test menunjukkan hasil positif, kemungkinannya ada dua, yaitu Anda benar terinfeksi Covid-19 atau terinfeksi virus lain, seperti demam berdarah, misalnya.

5. Kelebihan dan kekurangan pemeriksaan Swab dan PCR

Pengambilan spesimen lendir menggunakan swab dan pemeriksaan menggunakan PCR adalah metode yang paling akurat dalam mendeteksi virus SARS-COV2. Namun sayangnya, pemeriksaan ini membutuhkan waktu yang lebih lama dan lebih rumit. Pemeriksaan sampel pun hanya bisa dilakukan di laboratorium dengan kelengkapan khusus. Sehingga, kapasitas pemeriksaan tidak terlalu besar. Oleh karena itu, butuh waktu beberapa hari hingga hasil tes bisa keluar.

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